Dual mechanical valve thrombosis resolution through thrombolytics: a case series.
Colin McGuireMichael YangAlexander PapolosToby RogersBenjamin B KenigsbergPublished in: European heart journal. Case reports (2023)
Prosthetic valve thrombosis is a complex medical condition requiring a multi-disciplinary team to evaluate the best course of treatment. A trial of pharmacologic thrombolysis is often the first attempted treatment for obstructive PVT, although surgery is recommended for patients with NYHA IV symptoms, or with contraindications to thrombolysis, including high bleeding risk. However, in patients with high bleeding risk and NYHA Class III and IV heart failure, especially with surgical contraindications, low-dose thrombolytics, with slow or ultra-slow infusions, may still be safe and effective treatment strategies for multi-valve PVT. Further research is needed to guide thrombolysis in multi-valve PVT.
Keyphrases
- pulmonary embolism
- aortic valve
- mitral valve
- heart failure
- low dose
- aortic stenosis
- atrial fibrillation
- transcatheter aortic valve replacement
- healthcare
- minimally invasive
- clinical trial
- high resolution
- randomized controlled trial
- coronary artery bypass
- ejection fraction
- single molecule
- replacement therapy
- acute coronary syndrome
- breast cancer risk