Major contribution of the RNA-binding domain of NS1 in the pathogenicity and replication potential of an avian H7N1 influenza virus in chickens.

Sascha TrappDenis SoubieuxAlexandra LidoveEvelyne EsnaultAdrien LionVanaique GuilloryAlan WacquiezEmmanuel KutPascale QuéréThibaut LarcherMireille LedevinVirginie NadanChristelle Camus-BouclainvilleDaniel Marc

Published in: Virology journal (2018)

Collectively, our data emphasized the critical importance and essential role of the RNA-binding domain in essential steps of the virus replication cycle, notably expression and translation of viral mRNAs.

Keyphrases

disease virus
binding protein
poor prognosis
dna binding
sars cov
electronic health record
nucleic acid
dengue virus
big data
long non coding rna
transcription factor
data analysis
genome wide analysis