Decreased expression of SOX7 induces cell proliferation and invasion and correlates with poor prognosis in oral squamous cell carcinoma.

Kyu-Young OhKyoung-Ok HongYoung-Sung HuhJae-Il LeeSeong Doo Hong

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2017)

These results suggest that SOX7 inhibits cell proliferation, colony formation, and invasion in OSCC as a tumor suppressor and that negative SOX7 expression could be a poor prognostic indicator for patients with OSCC.

Keyphrases

poor prognosis
long non coding rna
transcription factor
stem cells
cell proliferation
single cell
cell therapy
cell cycle
cell migration
mesenchymal stem cells
pi k akt