Circulating Plasma Concentrations of ACE2 in Primary Aldosteronism and Cardiovascular Outcomes.
Vin-Cent WuKang-Yung PengYa-Hui HuChin-Chen ChangChieh-Kai ChanTai-Shuan LaiYen-Hung LinShuo-Meng WangChing-Chu LuYu-Chun LiuYao Chou TsaiShih-Chieh Jeff ChuehPublished in: The Journal of clinical endocrinology and metabolism (2022)
PA and EH patients had elevated pACE2 and higher expression of TMPRSS2 mRNA compared to those of normotensive population. Persistently elevated pACE2 (> 23 ng/mL) after targeted treatments was associated risk of mortality and incident cardiovascular events.