Eicosapentaenoic acid and Arachidonic acid Protection Against Left Ventricle Pathology: the Multi-Ethnic Study of Atherosclerosis.
Gregory C ShearerRobert C BlockShue HuangLinxi LiuDavid M HerringtonMichael Y TsaiNathan TintleTimothy D O'ConnellPublished in: medRxiv : the preprint server for health sciences (2024)
Plasma phospholipid AA and EPA are prospectively associated with indices of heart remodeling, including ventricular remodeling and performance. Combined AA and EPA scarcity was associated with the most accelerated age-related changes and exam 5 status, while the greatest benefits were found among participants with both PUFAs. This suggests that both PUFAs are required for optimal slowing of age-related declines in ventricular function.