Investigating the role of the IGF axis as a predictor of biochemical recurrence in prostate cancer patients post-surgery.
Kieran J BreenAmanda O'NeillLisa MurphyYue FanSusie BoyceNoel FitzgeraldEmma DorrisLauren BradyStephen P FinnBrian D HayesAnn TreacyCiara BarrettMardiana Abdul AzizElaine W KayJohn M FitzpatrickR William G WatsonPublished in: The Prostate (2017)
Low PTEN is associated with BCR and this association is strongly modified by high INSR and high AKT expression. Measurement of these proteins could help inform appropriate patient selection for postoperative adjuvant therapy and prevent BCR.
Keyphrases
- prostate cancer
- acute lymphoblastic leukemia
- end stage renal disease
- cell proliferation
- ejection fraction
- tyrosine kinase
- newly diagnosed
- minimally invasive
- chronic kidney disease
- poor prognosis
- signaling pathway
- pi k akt
- patients undergoing
- chronic myeloid leukemia
- radical prostatectomy
- binding protein
- case report
- patient reported outcomes
- coronary artery disease
- acute coronary syndrome