Association of DCIS size and margin status with risk of developing breast cancer post-treatment: multinational, pooled cohort study.
Renée S J M SchmitzAlexandra W van den Belt-DuseboutKaren ClementsYi RenChiara CrestaJasmine TimbresYat-Hee LiuDanalyn ByngThomas LynchBrian A MenegazDeborah CollyarTerry HyslopSamantha ThomasJason K LoveMichael SchaapveldProteeti BhattacharjeeMarc D RyserElinor SawyerE Shelley HwangAlastair ThompsonJelle WesselingEsther H LipsMarjanka K Schmidtnull nullPublished in: BMJ (Clinical research ed.) (2023)
The association of DCIS size and margin status with ipsilateral invasive breast cancer and ipsilateral DCIS was small. When these two factors were added to other known risk factors in multivariable models, clinicopathological risk factors alone were found to be limited in discriminating between low and high risk DCIS.