Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial.

Zhanjie ZhangBian WuGang PengGuixiang XiaoJing HuangQian DingChengzhang YangXingao XiongHui MaLiangliang ShiJinsong YangXiaohua HongJielin WeiYou QinChao WanYi ZhongYan ZhouXueyan ZhaoYangming LengTao ZhangGang WuMin YaoXiaomeng ZhangKunyu Yang

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Neoadjuvant chemotherapy plus camrelizumab for locally advanced HNSCC showed high ORR, pCR, and MPR rates, with an acceptable safety profile. These data support further evaluation of neoadjuvant chemoimmunotherapy for the treatment of locally advanced HNSCC.

Keyphrases

locally advanced
neoadjuvant chemotherapy
rectal cancer
squamous cell carcinoma
phase ii study
radiation therapy
clinical trial
lymph node
sentinel lymph node
randomized controlled trial
study protocol
open label
electronic health record
big data
deep learning
artificial intelligence
data analysis