Longitudinal drug synergy assessment using convolutional neural network image-decoding of glioblastoma single-spheroid cultures.

Anna GiczewskaKrzysztof PastuszakMegan HouwelingKulsoom U AbdulNoa FaaijLaurine WedekindDavid NoskeThomas WurdingerAnna SupernatBart A Westerman

Published in: Neuro-oncology advances (2023)

Our method facilitates longitudinal drug-interaction assessment, providing new insights into the temporal-dynamic effects of drug combinations in 3D neurospheres which can help to identify more effective therapies against glioblastoma.

Keyphrases

convolutional neural network
deep learning
adverse drug
cross sectional
drug induced