Immunomodulatory effects of probiotic supplementation in patients with asthma: a randomized, double-blind, placebo-controlled trial.

Sina SadrifarTannaz Abbasi-DokhtSarvenaz ForouzandehFarhad MalekBahman YousefiAmir Salek FarrokhiJafar KaramiRasoul Baharlou

Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2023)

In our study, 8-week treatment with probiotic supplementation led to reduced Th2 cells-associated IL-4 and improved Forced Expiratory Volume and Forced Vital Capacity. It appears probiotics can be used in addition to common asthma treatments.

Keyphrases

double blind
chronic obstructive pulmonary disease
placebo controlled
lung function
induced apoptosis
clinical trial
allergic rhinitis
cell cycle arrest
study protocol
phase iii
intensive care unit
lactic acid
mechanical ventilation
phase ii
oxidative stress
cell death
combination therapy
cell proliferation
pi k akt