Glutaredoxin 1 Downregulation in the Substantia Nigra Leads to Dopaminergic Degeneration in Mice.
Aditi VermaAjit RayDeepti BapatLatha DiwakarReddy Peera KommaddiBernard L SchneiderEtienne C HirschVijayalakshmi RavindranathPublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
Our study indicates that Grx1 is critical for the survival of SNpc DA neurons and that it is downregulated in human PD. © 2020 International Parkinson and Movement Disorder Society.