Elevated aqueous endothelin-1 concentrations in advanced diabetic retinopathy.
Hae Min KangMd HasanuzzamanSo Won KimHyoung Jun KohSung Chul LeePublished in: PloS one (2022)
The mean aqueous ET-1 level was significantly higher in the eyes with advanced DR than those with early DR and the control group. The mean aqueous ET-1 level was significantly reduced after intravitreal injections in the advanced DR group. Based on our results, future studies on the exact role of ET-1 in the pathogenesis of DR and future implication for intervention would be helpful for managing DR.