The Mechanism of Quercetin in the Treatment of Lung Squamous Cell Carcinoma Based on a Protein-Protein Interaction Network.

Yiping LuWenfeng ZhangHuayao LiCun LiuDandan GaoJing ZhuangRuijuan LiuJibiao Wu Changgang Sun

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

We found that QR not only inhibits the proliferation, migration, and invasion but also blocks the cell cycle progression of LUSC. QR downregulated the expression of the LUSC target gene PLK1 at the protein level.

Keyphrases

protein protein
cell cycle
small molecule
squamous cell carcinoma
cell proliferation
poor prognosis
binding protein
copy number
genome wide
radiation therapy
dna methylation
locally advanced
lymph node metastasis
combination therapy
amino acid
smoking cessation