Chemotherapy effectiveness in trial-underrepresented groups with early breast cancer: A retrospective cohort study.

Ewan GrayJoachim MartiJeremy C Wyatt David H BrewsterPeter S Hallnull null

Published in: PLoS medicine (2019)

The results of this study, as RWD, should be interpreted with caution and in the context of existing and emerging randomised data. The relative effectiveness of adjuvant chemotherapy in reducing mortality in patients with early stage breast cancer appears to be generalisable to the selected trial-underrepresented groups.

Keyphrases

study protocol
randomized controlled trial
clinical trial
early stage
early breast cancer
phase iii
phase ii
open label
systematic review
double blind
cardiovascular events
placebo controlled
big data
squamous cell carcinoma
risk factors
type diabetes
radiation therapy
neoadjuvant chemotherapy