Prescribed Antiseizure Medication Doses and Their Relation to Defined Daily Doses for Achieving Seizure Freedom in Newly Diagnosed Patients with Epilepsy.

Hire Hersi Jani Raitanen Jukka T SaarinenJukka Peltola

Published in: Epilepsia open (2023)

The present study provides new insights into the doses of the commonly used ASMs such as OXC, CBZ and VPA that can lead to seizure-freedom as monotherapy or as combination therapy. The higher PDD/DDD ratio of OXC (0.99) than that of CBZ or VPA renders a generalized PDD/DDD comparison highly problematic.

Keyphrases

combination therapy
newly diagnosed
temporal lobe epilepsy
physical activity
emergency department
randomized controlled trial
open label
study protocol
electronic health record