Acyl-Ethynylbenziodoxolone (acyl-EBX): Access to Ketene Dithioarylacetals.

Pierre PalaminiJulien BorrelMaël DjaïdMorgane DelattreJérôme Waser

Published in: Organic letters (2023)

We report the synthesis of ketene dithioarylacetals in 40-97% yield using thiophenols and acyl-EBXs (ethynylbenziodoxolones) generated in situ from a common hypervalent iodine precursor and alkynyl trifluoroborate salts. The products could be further modified to afford functionalized ketene dithioacetals and various S -substituted heterocycles.

Keyphrases

fatty acid
ionic liquid
fluorescent probe
magnetic resonance
computed tomography
molecularly imprinted
molecular dynamics simulations