LidocAine Versus Opioids In MyocarDial infarction: The AVOID-2 randomised controlled trial.
Himawan FernandoZiad NehmeCatherine MilneJessica O'BrienStephen BernardMichael StephensonPaul S MylesJeffrey LefkovitsKarlheinz PeterAngela BrennanDiem DinhEmily AndrewAndrew J TaylorKaren SmithDion Stubnull nullPublished in: European heart journal. Acute cardiovascular care (2022)
IV Lidocaine did not meet criteria for non-inferiority with lower prehospital pain reduction than fentanyl but was safe and better tolerated as analgesia in STEMI. Future trials testing non-opioid analgesics in STEMI and whether opioid avoidance improves clinical outcomes are needed.
Keyphrases
- pain management
- chronic pain
- percutaneous coronary intervention
- st elevation myocardial infarction
- st segment elevation myocardial infarction
- study protocol
- cardiac arrest
- heart failure
- left ventricular
- acute coronary syndrome
- coronary artery disease
- randomized controlled trial
- emergency medical
- ultrasound guided