Induced Pluripotent Stem Cell Modeling of Best Disease and Autosomal Recessive Bestrophinopathy.
Ji Hwan LeeJin Ok OhChristopher Seungkyu LeePublished in: Yonsei medical journal (2020)
A human iPSC model of ARB showed a functional deficiency rather than anatomical defects. ARB may be caused by RPE dysfunction following BEST1 mutation.