Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models.
Christian HotzTimothy R WagenaarFriederike GiesekeDinesh S BangariMichelle CallahanHui CaoJan DiekmannMustafa DikenChristian GrunwitzAndy HebertKarl HsuMarie BernardoKatalin KarikóSebastian KreiterAndreas N KuhnMikhail N LevitNatalia MalkovaSerena MasciariJack PollardHui QuSue RyanAbderaouf SelmiJulia SchlerethKuldeep SinghFangxian SunBodo TillmannTatiana TolstykhWilliam WeberLena WickeSonja WitzelQunyan YuYu-An ZhangGang ZhengJoanne LagerGary J NabelUğur ŞahinDmitri WiederschainPublished in: Science translational medicine (2021)
[Figure: see text].