Uğur Şahin (Ugur Sahin)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 29

Top Venues

Nature

Science (New York, N.Y.)

Science translational medicine

Science immunology

HI-TRON

This page only lists publications with an associated author ORCID identifier.

Affiliation History

HI-TRON Dec 01 2018

Germany

Director

TRON (Translational Oncology of the University Medical Center at the Johannes Gutenberg Universität Mainz)

Germany

Founder and Scientific Advisor

BioNTech

Germany

Co-founder and CEO

University Medical Center

Germany

Professor for Translational Oncology and Immunology :: Immunology

Publications

Christiane R Stadler, Ursula Ellinghaus, Leyla Fischer, Hayat Bähr-Mahmud, Martin Rao, Claudia Lindemann, Anuhar Chaturvedi, Caroline Scharf, Imke Biermann, Bernhard Hebich, Alexandra Malz, Georg Beresin, Georg Falck, Aline Häcker, Astrid Houben, Michael Erdeljan, Kristina Wolf, Maximilian Kullmann, Philip Chang, Özlem Türeci, Uğur Şahin
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell-engaging bispecific antibody targeting human claudin 6. Science translational medicine 16 (748) (2024)
Daniel Peters, Lena M Kranz, David Eisel, Mustafa Diken, Sebastian Kreiter, Özlem Tureci, Uğur Şahin, Mathias Vormehr
RNA-encoded interleukin-2 with extended bioavailability amplifies RNA vaccine-induced antitumor T-cell immunity. Cancer immunology research (2024)
Christiane R Stadler, Ursula Ellinghaus, Leyla Fischer, Hayat Bähr-Mahmud, Martin Rao, Claudia Lindemann, Anuhar Chaturvedi, Caroline Scharf, Imke Biermann, Bernhard Hebich, Alexandra Malz, Georg Beresin, Georg Falck, Aline Häcker, Astrid Houben, Michael Erdeljan, Kristina Wolf, Maximilian Kullmann, Philip Chang, Özlem Türeci, Uğur Şahin
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell-engaging bispecific antibody targeting human claudin 6. Science translational medicine 16 (748) (2024)
Hayat Bähr-Mahmud, Ursula Ellinghaus, Christiane R Stadler, Leyla Fischer, Claudia Lindemann, Anuhar Chaturvedi, Jan Diekmann, Stefan Wöll, Imke Biermann, Bernhard Hebich, Caroline Scharf, Manuela Siefke, Alexandra S Roth, Martin Rao, Kerstin Brettschneider, Eva-Maria Ewen, Uğur Şahin, Özlem Türeci
Preclinical characterization of an mRNA-encoded anti-Claudin 18.2 antibody. Oncoimmunology 12 (1) (2023)
Luis A Rojas, Zachary Sethna, Kevin C Soares, Cristina Olcese, Nan Pang, Erin Patterson, Jayon Lihm, Nicholas Ceglia, Pablo Guasp, Alexander Chu, Rebecca Yu, Adrienne Kaya Chandra, Theresa Waters, Jennifer Ruan, Masataka Amisaki, Abderezak Zebboudj, Zagaa Odgerel, George Payne, Evelyna Derhovanessian, Felicitas Müller, Ina Rhee, Mahesh Yadav, Anton Dobrin, Michel Sadelain, Marta Łuksza, Noah A Cohen, Laura Tang, Olca Basturk, Mithat Gönen, Seth Katz, Richard Kinh Do, Andrew S Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M Varghese, Elizabeth Won, Avni Desai, Alice C Wei, Michael I D'Angelica, T Peter Kingham, Ira Mellman, Taha Merghoub, Jedd D Wolchok, Uğur Şahin, Özlem Türeci, Benjamin D Greenbaum, William R Jarnagin, Jeffrey Drebin, Eileen M O'Reilly, Vinod P Balachandran
Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer. Nature (2023)
Andreas Mackensen, John B A G Haanen, Christian Koenecke, Winfried Alsdorf, Eva Maria Wagner-Drouet, Peter Borchmann, Daniel Heudobler, Barbara Ferstl, Sebastian Klobuch, Carsten Bokemeyer, Alexander Desuki, Florian Lüke, Nadine Kutsch, Fabian Müller, Eveline Smit, Peter Hillemanns, Panagiotis Karagiannis, Erol Wiegert, Ying He, Thang Ho, Qing Kang-Fortner, Anna Melissa Schlitter, Catrine Schulz-Eying, Andrew Finlayson, Carina Flemmig, Klaus Kühlcke, Liane Preußner, Benjamin Rengstl, Özlem Türeci, Uğur Şahin
CLDN6-specific CAR-T cells plus amplifying RNA vaccine in relapsed or refractory solid tumors: the phase 1 BNT211-01 trial. Nature medicine (2023)
Luis A Rojas, Zachary Sethna, Kevin C Soares, Cristina Olcese, Nan Pang, Erin Patterson, Jayon Lihm, Nicholas Ceglia, Pablo Guasp, Alexander Chu, Rebecca Yu, Adrienne Kaya Chandra, Theresa Waters, Jennifer Ruan, Masataka Amisaki, Abderezak Zebboudj, Zagaa Odgerel, George Payne, Evelyna Derhovanessian, Felicitas Müller, Ina Rhee, Mahesh Yadav, Anton Dobrin, Michel Sadelain, Marta Łuksza, Noah A Cohen, Laura Tang, Olca Basturk, Mithat Gönen, Seth Katz, Richard Kinh Do, Andrew S Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M Varghese, Elizabeth Won, Avni Desai, Alice C Wei, Michael I D'Angelica, T Peter Kingham, Ira Mellman, Taha Merghoub, Jedd D Wolchok, Uğur Şahin, Özlem Türeci, Benjamin D Greenbaum, William R Jarnagin, Jeffrey Drebin, Eileen M O'Reilly, Vinod P Balachandran
Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer. Nature (2023)
Florian Lordick, Peter C Thuss-Patience, Michael Bitzer, Daniel Maurus, Uğur Şahin, Özlem Tureci
Immunological effects and activity of multiple doses of zolbetuximab in combination with zoledronic acid and interleukin-2 in a phase 1 study in patients with advanced gastric and gastroesophageal junction cancer. Journal of cancer research and clinical oncology (2023)
Franziska Lang, Barbara Schrörs, Martin Löwer, Özlem Türeci, Uğur Şahin
Author Correction: Identification of neoantigens for individualized therapeutic cancer vaccines. Nature reviews. Drug discovery (2023)
Jasmin Quandt, Alexander Muik, Nadine Salisch, Bonny Gaby Lui, Sebastian Lutz, Kimberly Krüger, Ann-Kathrin Wallisch, Petra Adams-Quack, Maren Bacher, Andrew Finlayson, Orkun Ozhelvaci, Isabel Vogler, Katharina Grikscheit, Sebastian Hoehl, Udo Goetsch, Sandra Ciesek, Özlem Tureci, Uğur Şahin
Omicron BA.1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes. Science immunology 7 (75) (2022)
Franziska Lang, Barbara Schrörs, Martin Löwer, Özlem Türeci, Uğur Şahin
Identification of neoantigens for individualized therapeutic cancer vaccines. Nature reviews. Drug discovery 21 (4) (2022)
David Weber, Jonas Ibn-Salem, Patrick Sorn, Martin Suchan, Christoph Holtsträter, Urs Lahrmann, Isabel Vogler, Kathrin Schmoldt, Franziska Lang, Barbara Schrörs, Martin Löwer, Uğur Şahin
Accurate detection of tumor-specific gene fusions reveals strongly immunogenic personal neo-antigens. Nature biotechnology 40 (8) (2022)
Hanna Meister, Thomas Look, Patrick Roth, Natalia Teresa Jarzebska, Uğur Şahin, Sohyon Lee, Benjamin D Hale, Berend Snijder, Luca Regli, Vidhya Madapusi Ravi, Dieter Henrik Heiland, Charles L Sentman, Michael Weller, Tobias Weiss
Multifunctional mRNA-Based CAR T Cells Display Promising Antitumor Activity Against Glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (21) (2022)
Siri Tahtinen, Ann-Jay Tong, Patricia Himmels, Jaehak Oh, Andres Paler-Martinez, Leesun Kim, Sara Wichner, Yoko Oei, Mark J McCarron, Emily C Freund, Zhainib Adel Amir, Cecile C de la Cruz, Benjamin Haley, Craig Blanchette, Jill M Schartner, Weilan Ye, Mahesh Yadav, Uğur Şahin, Lélia Delamarre, Ira Mellman
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines. Nature immunology 23 (4) (2022)
Alexander Muik, Bonny Gaby Lui, Ann-Kathrin Wallisch, Maren Bacher, Julia Mühl, Jonas Reinholz, Orkun Ozhelvaci, Nina Beckmann, Ramón de la Caridad Güimil Garcia, Asaf Poran, Svetlana Shpyro, Andrew Finlayson, Hui Cai, Qi Yang, Kena A Swanson, Özlem Tureci, Uğur Şahin
Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine-elicited human sera. Science (New York, N.Y.) 375 (6581) (2022)
Alexander Muik, Bonny Gaby Lui, Maren Bacher, Ann-Kathrin Wallisch, Aras Toker, Carla Iris Cadima Couto, Alptekin Güler, Veena Mampilli, Geneva J Schmitt, Jonathan Mottl, Thomas Ziegenhals, Stephanie Fesser, Jonas Reinholz, Florian Wernig, Karla-Gerlinde Schraut, Hossam Hefesha, Hui Cai, Qi Yang, Kerstin C Walzer, Jessica Grosser, Stefan Strauss, Andrew Finlayson, Kimberly Krüger, Orkun Ozhelvaci, Katharina Grikscheit, Niko Kohmer, Sandra Ciesek, Kena A Swanson, Annette B Vogel, Özlem Türeci, Uğur Şahin
Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice. Science immunology (2022)
Matthias Birtel, Ralf-Holger Voss, Katharina Reinhard, Benjamin Rengstl, Yasmina Ouchan, Kristina Michel, Nina Hayduk, Bodo Tillmann, René Becker, Martin Suchan, Matthias Theobald, Petra Oehm, Özlem Türeci, Uğur Şahin
A TCR-like CAR Promotes Sensitive Antigen Recognition and Controlled T-cell Expansion Upon mRNA Vaccination. Cancer research communications 2 (8) (2022)
Alexander Muik, Bonny Gaby Lui, Maren Bacher, Ann-Kathrin Wallisch, Aras Toker, Andrew Finlayson, Kimberly Krüger, Orkun Ozhelvaci, Katharina Grikscheit, Sebastian Hoehl, Sandra Ciesek, Özlem Türeci, Uğur Şahin
Omicron BA.2 breakthrough infection enhances cross-neutralization of BA.2.12.1 and BA.4/BA.5. Science immunology 7 (77) (2022)
Gary R McLean, Jeremy P Kamil, Benhur Lee, Penny L Moore, Thomas F Schulz, Alexander Muik, Uğur Şahin, Özlem Türeci, Shanti Pather
The Impact of Evolving SARS-CoV-2 Mutations and Variants on COVID-19 Vaccines. mBio 13 (2) (2022)
Christian Hotz, Timothy R Wagenaar, Friederike Gieseke, Dinesh S Bangari, Michelle Callahan, Hui Cao, Jan Diekmann, Mustafa Diken, Christian Grunwitz, Andy Hebert, Karl Hsu, Marie Bernardo, Katalin Karikó, Sebastian Kreiter, Andreas N Kuhn, Mikhail N Levit, Natalia Malkova, Serena Masciari, Jack Pollard, Hui Qu, Sue Ryan, Abderaouf Selmi, Julia Schlereth, Kuldeep Singh, Fangxian Sun, Bodo Tillmann, Tatiana Tolstykh, William Weber, Lena Wicke, Sonja Witzel, Qunyan Yu, Yu-An Zhang, Gang Zheng, Joanne Lager, Gary J Nabel, Uğur Şahin, Dmitri Wiederschain
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models. Science translational medicine 13 (610) (2021)
Miwa Haranaka, James Baber, Yoichiro Ogama, Masako Yamaji, Masakazu Aizawa, Osamu Kogawara, Ingrid L Scully, Eleni Lagkadinou, Özlem Tureci, Uğur Şahin, Philip R Dormitzer, William C Gruber, Stephen Lockhart
A randomized study to evaluate safety and immunogenicity of the BNT162b2 COVID-19 vaccine in healthy Japanese adults. Nature communications 12 (1) (2021)
Uğur Şahin, Alexander Muik, Isabel Vogler, Evelyna Derhovanessian, Lena M Kranz, Mathias Vormehr, Jasmin Quandt, Nicole Bidmon, Alexander Ulges, Alina Baum, Kristen E Pascal, Daniel Maurus, Sebastian Brachtendorf, Verena Lörks, Julian Sikorski, Peter Koch, Rolf Hilker, Dirk Becker, Ann-Kathrin Eller, Jan Grützner, Manuel Tonigold, Carsten Boesler, Corinna Rosenbaum, Ludwig Heesen, Marie-Cristine Kühnle, Asaf Poran, Jesse Z Dong, Ulrich Luxemburger, Alexandra Kemmer-Brück, David Langer, Martin Bexon, Stefanie Bolte, Tania Palanche, Armin Schultz, Sybille Baumann, Azita J Mahiny, Gábor Boros, Jonas Reinholz, Gábor Tamás Szabó, Katalin Karikó, Pei-Yong Shi, Camila R Fontes-Garfias, John L Perez, Mark Cutler, David Cooper, Christos A Kyratsous, Philip R Dormitzer, Kathrin U Jansen, Özlem Türeci
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans. Nature 595 (7868) (2021)
Jan D Beck, Daniel Peters, Nadja Salomon, Uğur Şahin, Özlem Türeci, Mathias Vormehr, Lena M Kranz
mRNA therapeutics in cancer immunotherapy. Molecular cancer 20 (1) (2021)
Alexander Muik, Ann-Kathrin Wallisch, Bianca Sänger, Kena A Swanson, Julia Mühl, Wei Chen, Hui Cai, Daniel Maurus, Ritu Sarkar, Özlem Tureci, Philip R Dormitzer, Uğur Şahin
Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine-elicited human sera. Science (New York, N.Y.) 371 (6534) (2021)
Uğur Şahin, Petra Oehm, Evelyna Derhovanessian, Robert A Jabulowsky, Mathias Vormehr, Maike Gold, Daniel Maurus, Doreen Schwarck-Kokarakis, Andreas N Kuhn, Tana Omokoko, Lena M Kranz, Mustafa Diken, Sebastian Kreiter, Heinrich Haas, Sebastian Attig, Richard Rae, Katarina Cuk, Alexandra Kemmer-Brück, Andrea Breitkreuz, Claudia Tolliver, Janina Caspar, Juliane Quinkhardt, Lisa Hebich, Malte Stein, Alexander Hohberger, Isabel Vogler, Inga Liebig, Stephanie Renken, Julian Sikorski, Melanie Leierer, Verena Müller, Heidrun Mitzel-Rink, Matthias Miederer, Christoph Huber, Stephan Grabbe, Jochen Utikal, Andreas Pinter, Roland Kaufmann, Jessica C Hassel, Carmen Loquai, Özlem Türeci
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma. Nature 585 (7823) (2020)
Katharina Reinhard, Benjamin Rengstl, Petra Oehm, Kristina Michel, Arne Billmeier, Nina Hayduk, Oliver Klein, Kathrin Kuna, Yasmina Ouchan, Stefan Wöll, Elmar Christ, David Weber, Martin Suchan, Thomas Bukur, Matthias Birtel, Veronika Jahndel, Karolina Mroz, Kathleen Hobohm, Lena Kranz, Mustafa Diken, Klaus Kühlcke, Özlem Tureci, Uğur Şahin
An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors. Science (New York, N.Y.) 367 (6476) (2020)
Mark J Mulligan, Kirsten E Lyke, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen Lockhart, Kathleen Neuzil, Vanessa Raabe, Ruth Bailey, Kena A Swanson, Ping Li, Kenneth Koury, Warren Kalina, David Cooper, Camila Fontes-Garfias, Pei-Yong Shi, Özlem Türeci, Kristin R Tompkins, Edward E Walsh, Robert Frenck, Ann R Falsey, Philip R Dormitzer, William C Gruber, Uğur Şahin, Kathrin U Jansen
Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults. Nature 586 (7830) (2020)
Uğur Şahin, Alexander Muik, Evelyna Derhovanessian, Isabel Vogler, Lena M Kranz, Mathias Vormehr, Alina Baum, Kristen E Pascal, Jasmin Quandt, Daniel Maurus, Sebastian Brachtendorf, Verena Lörks, Julian Sikorski, Rolf Hilker, Dirk Becker, Ann-Kathrin Eller, Jan Grützner, Carsten Boesler, Corinna Rosenbaum, Marie-Cristine Kühnle, Ulrich Luxemburger, Alexandra Kemmer-Brück, David Langer, Martin Bexon, Stefanie Bolte, Katalin Karikó, Tania Palanche, Boris Fischer, Armin Schultz, Pei-Yong Shi, Camila Fontes-Garfias, John L Perez, Kena A Swanson, Jakob Loschko, Ingrid L Scully, Mark Cutler, Warren Kalina, Christos A Kyratsous, David Cooper, Philip R Dormitzer, Kathrin U Jansen, Özlem Türeci
COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses. Nature 586 (7830) (2020)
Uğur Şahin, Özlem Türeci
Personalized vaccines for cancer immunotherapy. Science (New York, N.Y.) 359 (6382) (2018)

Uğur Şahin.css-eqlu8i{font-size:small;padding-left:4px;} (Ugur Sahin)

Publication Activity (10 Years)

Top Topics

Top Venues

Uğur Şahin (Ugur Sahin)