Association of Depression Onset and Treatment With Blood Pressure Control After Intracerebral Hemorrhage.
Sophia KeinsJessica R AbramsonAkashleena MallickJuan Pablo CastelloAxana Rodriguez-TorresDominique L PopescuDanielle HoffmanChristina KourkoulisMahmut Edip GurolSteven M GreenbergChristopher D AndersonAnand ViswanathanJonathan RosandAlessandro BiffiPublished in: Stroke (2022)
ICH survivors displayed increasing BP values after receiving a diagnosis of depression, followed by decreasing values among those experiencing resolution of depressive symptoms. Use of selective serotonin reuptake inhibitor and noradrenaline-serotonin reuptake inhibitor antidepressants was independently associated with higher systolic BP measurements. Clinicians ought to closely monitor BP for ICH survivors being treated for depression, especially using selective serotonin reuptake inhibitor and noradrenaline-serotonin reuptake inhibitor. Future studies will also be required to investigate the mechanisms underlying these associations.