Association of adipocyte size and SREBP-1c in visceral and subcutaneous adipose tissue in non-obese type 2 diabetes mellitus.

Pieu AdhikarySudipta BanerjeeBishal Kumar DeyPiyas GargariShamita ChatterjeeDiya ChakrabortySubhankar Chowdhury

Published in: Endocrine (2023)

Reduced expression of SREBP-1c in preadipocytes may lead to increased number of hypertrophied adipocytes in T2DM. Therefore, these dysfunctional hypertrophied adipocytes could cause imbalanced expression of insulin resistant and insulin sensitive adipokines.

Keyphrases

adipose tissue
insulin resistance
glycemic control
type diabetes
poor prognosis
high fat diet
metabolic syndrome
long non coding rna
cardiovascular disease
bariatric surgery