Reduction of oxidative stress improves insulin signaling in cardiac tissue of obese mice.
Matheus Scarpatto RodriguesBruno Luiz da Silva PieriGustavo de Bem SilveiraRubya Pereira ZaccaronLigia Milanez VenturiniVitor Hugo CominKarine Damian LuizPaulo Cesar Lock SilveiraPublished in: Einstein (Sao Paulo, Brazil) (2020)
Obesity and/or a high-lipid diet may result in oxidative stress and insulin resistance in the heart tissue of obese mice, and the use of N-acetylcysteine as a methodological and therapeutic strategy suggested there is a relation between them.
Keyphrases
- oxidative stress
- type diabetes
- weight loss
- dna damage
- metabolic syndrome
- insulin resistance
- ischemia reperfusion injury
- diabetic rats
- heart failure
- induced apoptosis
- physical activity
- left ventricular
- atrial fibrillation
- weight gain
- glycemic control
- high fat diet induced
- fatty acid
- heat shock
- heat stress
- endoplasmic reticulum stress