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Effect of Radio-Chemotherapy on PD-L1 Immunohistochemical Expression in Head and Neck Squamous Cell Carcinoma.

Ilaria GirolamiStefano MarlettaVincenzo FiorentinoSimonetta BattocchioBruna CerbelliBarbara FiamengoClara GerosaAndrea GianattiLuca MorelliGiulio RivaMaria Giovanna ZagamiNicola FuscoEnrico MunariVincenzo L'ImperioFabio PagniPatrizia MorbiniMaurizio MartiniAlbino Eccher
Published in: Journal of personalized medicine (2023)
From the present evidence, a clear conclusion towards an increase or decrease in PD-L1 expression after combined therapy cannot be drawn, but even with few studies available, a trend towards an increase in expression in tumor cells at a cutoff of 1% can be noted in patients undergoing platinum-based therapy. Future studies will provide more robust data on the effect of combined therapy on PD-L1 expression.
Keyphrases
  • patients undergoing
  • poor prognosis
  • stem cells
  • electronic health record
  • machine learning
  • mesenchymal stem cells
  • bone marrow
  • case control
  • cell therapy
  • rectal cancer