Effect of Adolescent Bariatric Surgery on the Brain and Cognition: A Pilot Study.
Alaina L PearceEleanor MackeyJ Bradley C CherryAlexandra OlsonXiaozhen YouSheela N MaggeMichele Mietus-SnyderEvan P NadlerChandan J VaidyaPublished in: Obesity (Silver Spring, Md.) (2018)
Results provide pilot evidence for functional brain changes induced by VSG in adolescents with severe obesity. Weight loss and gain were paralleled by reduced and increased prefrontal activation, respectively, suggesting neural plasticity related to metabolic change.
Keyphrases
- weight loss
- bariatric surgery
- white matter
- young adults
- resting state
- functional connectivity
- roux en y gastric bypass
- obese patients
- gastric bypass
- insulin resistance
- mental health
- metabolic syndrome
- type diabetes
- physical activity
- weight gain
- cerebral ischemia
- working memory
- mild cognitive impairment
- early onset
- study protocol
- randomized controlled trial
- drug induced
- blood brain barrier
- childhood cancer
- body mass index