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An in-silico study examining the induction of apoptosis by Cryptotanshinone in metastatic melanoma cell lines.

Radhika S SarafAniruddha DattaChao SimaJianping HuaRosana LopesMichael Bittner
Published in: BMC cancer (2018)
The results presented in this paper facilitate a better understanding of melanoma drug resistance. Furthermore, this framework can be used to detect additional drug intervention points in the pathway that could amplify the action of Cryptotanshinone.
Keyphrases
  • randomized controlled trial
  • oxidative stress
  • endoplasmic reticulum stress
  • cell death
  • molecular docking
  • cell cycle arrest
  • cell proliferation
  • skin cancer
  • pi k akt