Switching to Once-Weekly Insulin Icodec Versus Once-Daily Insulin Glargine U100 in Type 2 Diabetes Inadequately Controlled on Daily Basal Insulin: A Phase 2 Randomized Controlled Trial.
Harpreet S BajajRichard M BergenstalAndreas ChristoffersenMelanie J DaviesAmoolya GowdaJoakim IsendahlIldiko LingvayPeter A SeniorRobert J SilverRoberto TrevisanJulio RosenstockPublished in: Diabetes care (2021)
Switching from daily basal insulin to once-weekly icodec was well tolerated and provided effective glycemic control. Loading dose use when switching to once-weekly icodec significantly increased percent TIR during weeks 15 and 16 versus once-daily IGlar U100, without increasing hypoglycemia risk.