Association of CRISPR/Cas System with the Drug Resistance in Klebsiella pneumoniae.
Gang WangGuobin SongYuanhong XuPublished in: Infection and drug resistance (2020)
ESBL-producing and carbapenem-resistant K. pneumoniae are more likely to develop multidrug resistance and show an inverse correlation between drug resistance and CRISPR/Cas system. Absence of CRISPR/Cas modules allow for the acquisition of external drug resistance genes.