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Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles.

Rayner González-PrendesRaquel QuintanillaEmilio Mármol-SánchezRamona N PenaMaria BallesterTainã Figueiredo CardosoArianna ManunzaJoaquim CasellasÁngela CánovasIsabel DíazJosé Luis NogueraAnna CastellóAnna MercadéMarcel Amills
Published in: BMC genomics (2019)
We have detected significant differences in the mRNA expression patterns of the porcine LD and GM muscles, evidencing that the transcriptomic profile of the skeletal muscle tissue is affected by anatomical, metabolic and functional factors. A highly significant association with IMF composition on SSC14 was replicated in both muscles, highlighting the existence of a common genetic determinism, but we also observed the existence of a few associations whose magnitude and significance varied between LD and GM muscles.
Keyphrases
  • skeletal muscle
  • genome wide
  • adipose tissue
  • insulin resistance
  • single cell
  • gene expression
  • dna methylation
  • fatty acid
  • rna seq