GIP attenuates neuronal oxidative stress by regulating glucose uptake in spinal cord injury of rat.
Beibei GuoMengwei QiXiaoqian LuoLongyu GuoMan XuYufang ZhangZhen LiMingxuan LiRonghua WuTuchen GuanMei LiuYan LiuPublished in: CNS neuroscience & therapeutics (2024)
GIP increases GLUT3 expression and promotes glucose intake in neurons, which exerts an antioxidant effect and protects neuronal cells from oxidative stress both in vitro and in vivo.
Keyphrases
- oxidative stress
- spinal cord injury
- spinal cord
- diabetic rats
- ischemia reperfusion injury
- dna damage
- blood glucose
- induced apoptosis
- poor prognosis
- cerebral ischemia
- neuropathic pain
- binding protein
- heat shock
- type diabetes
- blood pressure
- skeletal muscle
- subarachnoid hemorrhage
- adipose tissue
- blood brain barrier
- weight loss