Metabolic insights into HIV/TB co-infection: an untargeted urinary metabolomics approach.
Cara OlivierLaneke LuiesPublished in: Metabolomics : Official journal of the Metabolomic Society (2024)
Metabolic profiling revealed a unique metabolic landscape shaped by HIV/TB co-infection. The findings highlight the potential of urinary differential metabolites for co-infection, offering a non-invasive tool for enhancing diagnostic precision and tailoring therapeutic interventions. Future research should focus on expanding sample sizes and integrating longitudinal analyses to build upon these foundational insights, paving the way for metabolomic applications in combating these concurrent pandemics.
Keyphrases
- antiretroviral therapy
- hiv positive
- hiv infected
- human immunodeficiency virus
- single cell
- hepatitis c virus
- mass spectrometry
- hiv testing
- mycobacterium tuberculosis
- hiv aids
- men who have sex with men
- physical activity
- south africa
- squamous cell carcinoma
- current status
- cross sectional
- locally advanced
- climate change
- gas chromatography mass spectrometry