Challenges in evaluating pelvic floor physiotherapy based strategies in low anterior resection syndrome: a systematic review and qualitative analysis.
Lauren J LambrineasHenry G BrockHwa Ian OngSantha TisseverasingheEmma CarringtonAlexander HeriotAdele BurgessDavid ProudHelen MohanPublished in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2024)
Upcoming trial design in the area of pelvic floor physiotherapy for faecal incontinence related to rectal cancer surgery can be cognisant of and design around the challenges identified in this systematic review, including the reduction of bias, exclusion of the placebo effect and the potential cultural differences in attitude towards a sensitive intervention.
Keyphrases
- systematic review
- rectal cancer
- phase iii
- minimally invasive
- meta analyses
- randomized controlled trial
- clinical trial
- locally advanced
- coronary artery bypass
- study protocol
- phase ii
- open label
- squamous cell carcinoma
- double blind
- risk assessment
- coronary artery disease
- acute coronary syndrome
- climate change
- data analysis