Systemic antibody response to nano-size calcium phospate biocompatible adjuvant adsorbed HEV-71 killed vaccine.
Mohamed Ibrahim SaeedAbdul Rahman Bin OmarMohd Zobir HusseinIsam Mohamed ElkhidirZamberi SekawiPublished in: Clinical and experimental vaccine research (2015)
The intradermal vaccine adsorbed CaP nano-adjuvant showed safer and significant antibody response after one-tenth reduced dose quantity (0.5 µg/mL) of only 0.1-mL volume as the most suitable protective, cost effective and affordable formulation not only for HEV-71; but also for developing further effective vaccines toward other human pathogens.