Is there a relationship between phosphodiesterase type 5 inhibitors and biochemical recurrence after radical prostatectomy: a systematic review and meta-analysis.

Qing HeBang-Hua LiaoKai-Wen XiaoLiang ZhouShi-Jian FengHong LiKun-Jie Wang

Published in: International urology and nephrology (2018)

Our meta-analysis indicated that PDE5I treatment in men following RP did not increase the risk of BCR. The results preliminarily suggested that the use of PDE5I for erectile dysfunction after RP was oncologically safe. Nevertheless, more large sample cohort studies are needed to validate this conclusion.

Keyphrases

radical prostatectomy
prostate cancer
systematic review
acute lymphoblastic leukemia
meta analyses
tyrosine kinase
randomized controlled trial
combination therapy
replacement therapy