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Non-alcoholic fatty liver disease and increased risk of incident extrahepatic cancers: a meta-analysis of observational cohort studies.

Alessandro MantovaniGraziana PetraccaGiorgia BeatriceAlessandro CsermelyHerbert TilgChristopher D ByrneGiovanni Targher
Published in: Gut (2021)
This large meta-analysis suggests that NAFLD is associated with a moderately increased long-term risk of developing extrahepatic cancers over a median of nearly 6 years (especially GI cancers, breast cancer and gynaecological cancers). Further research is required to decipher the complex link between NAFLD and cancer development.
Keyphrases
  • systematic review
  • childhood cancer
  • papillary thyroid
  • cardiovascular disease
  • randomized controlled trial
  • squamous cell
  • lymph node metastasis
  • case control