The augmentation of cytotoxic immune cell functionality through physical exertion bolsters the potency of chemotherapy in models of mammary carcinoma.
Bingqing QinZhongshi HeLixia XieShenglan FengJunjie YeJianjun GuiXiaodong SunMing SangPublished in: Cancer medicine (2024)
Physical training improves the effectiveness of doxorubicin in treating breast cancer by activating cytotoxic immune cells, releasing tumor suppressor factors, and initiating mt-apoptosis, all while mitigating the adverse effects of chemotherapy.
Keyphrases
- physical activity
- locally advanced
- mental health
- randomized controlled trial
- oxidative stress
- signaling pathway
- systematic review
- endoplasmic reticulum stress
- cell cycle arrest
- drug delivery
- cell death
- cancer therapy
- squamous cell carcinoma
- emergency department
- chemotherapy induced
- rectal cancer
- soft tissue
- radiation therapy
- cell proliferation
- pi k akt
- adverse drug
- anti inflammatory
- breast cancer risk