Treatment of pediatric pulmonary arterial hypertension: A focus on the NO-sGC-cGMP pathway.

Maurice Beghetti Matthias Gorenflo D Dunbar Ivy Shahin Moledina Damien Bonnet

Published in: Pediatric pulmonology (2019)

The pooling of data across trials, supplemented by registry data, will help to confirm the safety and tolerability of prostanoids, ERAs, and PDE5i in children. Ongoing studies will clarify the place of sGC stimulators in the treatment strategy for pediatric PAH.

Keyphrases

pulmonary arterial hypertension
electronic health record
big data
randomized controlled trial
machine learning
coronary artery
data analysis
placebo controlled