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Impact of Guideline-Discordant Treatment on Cost and Health Care Utilization in Older Adults with Early-Stage Breast Cancer.

Courtney P WilliamsKelly M KenzikAndres AzueroGrant R WilliamsMaria PisuKarina I HalilovaStacey A IngramSupriya K YagnikAndres ForeroSmita BhatiaGabrielle B Rocque
Published in: The oncologist (2018)
Previous studies lack details about types of deviations from chemotherapy guidelines that occur in older early-stage breast cancer patients. Understanding the patterns of guideline discordance and its impact on patient outcomes will be particularly important for these patients. This study found 16% received guideline-discordant care, predominantly related to reduced intensity treatment and associated with higher costs and rates of health care utilization. Increasing older adult participation in clinical trials should be a priority in order to fill the knowledge gap about how to treat older, less fit patients with breast cancer.
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