Exploring the success of Brazilian endemic clone Pseudomonas aeruginosa ST277 and its association with the CRISPR-Cas system type I-C.

Melise Chaves SilveiraCláudio Marcos Rocha-de-SouzaRodolpho Mattos AlbanoIvson Cassiano de Oliveira SantosAna Paula D' Alincourt Carvalho Assef

Published in: BMC genomics (2020)

Based on our findings, P. aeruginosa ST277 strains circulating in Brazil characteristically acquired In163 and PAGI-25, which can distinguish them from strains that do not accumulate resistance mechanisms and can be found on the Asian, European and North American continents. The distinctive genetic elements accumulated in Brazilian samples can contribute to the resistance, pathogenicity and transmission success that characterize the ST277 in this country.

Keyphrases

crispr cas
pseudomonas aeruginosa
escherichia coli
genome editing
biofilm formation
cystic fibrosis
genome wide
multidrug resistant