Single intravitreal aflibercept injection for unilateral acute nonarteritic ischemic optic neuropathy.
Ziya AyhanGamze KocaoğluAylin YamanMeltem Söylev BajinA Osman SaatciPublished in: Case reports in ophthalmological medicine (2015)
Acute nonarteritic ischemic optic neuropathy (ANAION) is the most common optic neuropathy in the elderly population without a well-established treatment. A 67-year-old man with a sudden painless visual loss in his left eye of one-day duration was diagnosed to have left ANAION. Next day, 2 mg aflibercept injection was injected intravitreally in OS. Visual acuity improved to 7/10 from 1/10 a week after the injection. Mean retinal nerve fiber layer thickness (RNFLT) was reduced to 159,7 μm from 182,4 μm at the first week. Visual fields improved dramatically during the follow-up of three months. The aim of this study is to present a case having ANAION treated with a single intravitreal aflibercept injection and discuss the place of intravitreal anti-VEGF injections in the treatment of armamentarium of ANAION.
Keyphrases
- age related macular degeneration
- vascular endothelial growth factor
- ultrasound guided
- diabetic retinopathy
- liver failure
- optical coherence tomography
- respiratory failure
- endothelial cells
- combination therapy
- randomized controlled trial
- ischemia reperfusion injury
- aortic dissection
- extracorporeal membrane oxygenation
- middle aged
- hepatitis b virus
- cerebral ischemia
- newly diagnosed