Laser Therapy as a Preventive Approach for Oral Mucositis in Cancer Patients Undergoing Chemotherapy: The Potential Role of Superoxide Dismutase.
Beatriz Coutens De MenezesMarcela Marçal ThebitLucas André Silva BonelaKarine Gadioli De OliveiraWashington Luiz GonçalvesNazare Souza BissoliCarmem Luiza SartorioSonia Alves GouveaPublished in: Asian Pacific journal of cancer prevention : APJCP (2021)
The prophylactic laser therapy protocol proposed by the study, defined at a frequency of 630nm, a dose of 2J / cm2, demonstrated the ability to decrease the occurrence of oral mucositis in patients undergoing chemotherapy protocols to solid tumors. This effect could be related to preserved SOD activity, as it was observed that oral mucositis is related to leukopenia and reduced SOD activity and LLLT protocol prevented the decrease of SOD activity.