Comparing two identically protocolized, multicentre, randomized controlled trials on caregiver-mediated exercises poststroke: Any differences across countries?
Marijn MulderRinske H M NijlandJudith D M VloothuisMaayken van den BergMaria CrottyGert KwakkelErwin E H van WegenPublished in: PloS one (2022)
The present study highlighted important clinical differences across countries whilst using an identical study protocol. The observed differences could result in a different potential for recovery and variation in treatment effects across trials. We argue that we can proceed faster to evaluating interventions within international pragmatic trials.