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Bayesian Estimation of Human Population Toxicokinetics of PFOA, PFOS, PFHxS, and PFNA from Studies of Contaminated Drinking Water.

Weihsueh A ChiuMeghan T LynchClaire R LayAdriana AntezanaParker MalekSara SokolinskiRachel D Rogers
Published in: Environmental health perspectives (2022)
These results have direct application in both risk assessment (quantitative interspecies extrapolation and uncertainty factors for interindividual variability) and risk communication (interpretation of monitoring data). In addition, this study provides a rigorous methodology for further refinement with additional data, as well as application to other PFAS. https://doi.org/10.1289/EHP10103.
Keyphrases
  • drinking water
  • risk assessment
  • electronic health record
  • health risk assessment
  • health risk
  • heavy metals
  • endothelial cells
  • big data
  • high resolution
  • pluripotent stem cells
  • mass spectrometry
  • climate change