TRAX Provides Neuroprotection for Huntington's Disease Via Modulating a Novel Subset of MicroRNAs.

Yu-Ting WengHui-Mei ChenTing ChienFeng-Lan ChiuHung-Chih KuoYijuang Chern

Published in: Movement disorders : official journal of the Movement Disorder Society (2022)

We demonstrated that TRAX upregulation is authentic and protective in HD. Our study provides a novel layer of regulation for HD pathogenesis and may lead to the development of new therapeutic strategies for HD. © 2022 International Parkinson and Movement Disorder Society.

Keyphrases

signaling pathway
cell proliferation
poor prognosis
brain injury
long non coding rna