Probabilistic Linkage of Randomized Controlled Trial Data to Administrative Claims: A Case Study of Patients from Baricitinib Clinical Trials.
Catherine B McGuinessNatalie N BoytsovXiang ZhangCatherine B McGuinessCarol L KannowskiRolin L WadePublished in: Rheumatology and therapy (2021)
This probabilistic linkage methodology demonstrates the feasibility, at a moderate linkage rate, of linking patients from RCTs to real-world data, which can provide a means to assess additional information not usually collected within or following a clinical trial.
Keyphrases
- clinical trial
- randomized controlled trial
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- study protocol
- prognostic factors
- healthcare
- gene expression
- big data
- patient reported outcomes
- hepatitis c virus
- open label
- human immunodeficiency virus
- artificial intelligence
- patient reported
- deep learning