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A pilot study of the effect of phospholipid curcumin on serum metabolomic profile in patients with non-alcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.

Saeed ChashmniamSeyed Reza MirhafezMaryam DehabehMitra HaririMohsen Azimi NezhadB Fatemeh Nobakht M Gh
Published in: European journal of clinical nutrition (2019)
Characterizing the serum metabolic profile of the patients with NAFLD at the end of the intervention using NMR-based metabolomics method indicated that the targets of curcumin treatment included some amino acids, TCA cycle, bile acids, and gut microbiota.
Keyphrases
  • double blind
  • amino acid
  • randomized controlled trial
  • clinical trial
  • placebo controlled
  • study protocol
  • magnetic resonance
  • mass spectrometry
  • high resolution
  • phase ii
  • liver fibrosis