Real-world study of tenofovir disoproxil fumarate to prevent hepatitis B transmission in mothers with high viral load.

Ming WangQian BianYunxia ZhuQiumei PangLingzhi ChangRan LiBenjamin C TiongsonHua ZhangCalvin Qian Pan

Published in: Alimentary pharmacology & therapeutics (2018)

TDF for highly viraemic mothers was well tolerated and reduced vertical transmission of HBV in a real-world setting. There were no safety concerns during the postpartum 28-week follow-up. Registry number: Chinese Clinical Trial Registration No. ChiCTR-OIC-17010869.

Keyphrases

clinical trial
hepatitis b virus
randomized controlled trial
study protocol
antiretroviral therapy
liver failure