Apelin enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly through Wnt/β-catenin signaling pathway.

Kai HangChenyi YeJianxiang XuErman ChenCong WangWei ZhangLic NiZhih KuangLi YingDeting XueZhi-Jun Pan

Published in: Stem cell research & therapy (2019)

Taken together, these findings indicate that Apelin regulates osteogenic differentiation of hMSCs partly via the Wnt/β-catenin signaling pathway and effectively promotes fracture healing.

Keyphrases

cell proliferation
stem cells
endothelial cells
induced pluripotent stem cells
pluripotent stem cells