A review of available software for adaptive clinical trial design.

Michael John Grayling Graham Mark Wheeler

Published in: Clinical trials (London, England) (2020)

There is much room for improvement in the provision of software alongside adaptive design publications. In addition, while progress has been made, well-established software for various types of trial adaptation remains sparsely available.

Keyphrases

clinical trial
phase ii
study protocol
data analysis
phase iii
open label
palliative care
randomized controlled trial
double blind