Expression Patterns of Xenobiotic-Metabolizing Enzymes in Tumor and Adjacent Normal Mucosa Tissues among Patients with Colorectal Cancer: The ColoCare Study.
Jolantha BeyerleAndreana N HolowatyjMariam HaffaEva FreiBiljana GigicPetra Schrotz-KingJuergen BoehmNina HabermannMarie StiborovaDominique SchererTorsten KölschStephanie SkenderNikolaus BeckerEsther HerpelMartin SchneiderAlexis UlrichPeter SchirmacherJenny Chang-ClaudeHermann BrennerMichael HoffmeisterUlrike HaugRobert W OwenCornelia M UlrichPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)
Better understanding into the role of drug-metabolizing enzymes in colorectal cancer may reveal biological differences that contribute to cancer development, as well as treatment response, leading to clinical implications in colorectal cancer prevention and management.